Pathology, Physiology. a hardened or thickened part of the skin; a callosity. a new growth of osseous matter at the ends of a fractured bone, serving to unite them.
Also, callose. Botany. the tissue that forms over the wounds of plants, protecting the inner tissues and causing healing. a deposit on the perforated area of a sieve tube. (in grasses) a tough swelling at the base of a lemma or palea.
to form a callus.
to produce a callus or calluses on: Heavy work callused his hands.
Also called callosity. an area of skin that is hard or thick, esp on the palm of the hand or sole of the foot, as from continual friction or pressure